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目的 :总结X刀治疗脑转移瘤临床效果。方法 :X刀治疗脑转移瘤 5 8例 ,共 78个病灶 ,肿瘤周边剂量平均为 19 73Gy ,一般以 70 %～ 10 0 %等剂量线覆盖肿瘤周边 ,2 8例患者配合全脑放疗。结果 :随访 3～ 2 6个月 ,CT和MRI随访 47例 ,证实肿瘤治疗后完全消失 (CR) 2 0例( 42 6% ) ,大部分消失 (PR) 8例 ( 17 0 % ) ,部分消失 (MR) 8例 ( 17 0 % ) ,无变化 (NC) 6例 ( 12 8% ) ,增大 (PG) 5例 ( 10 6% ) ;脑水肿反应严重 3例。临床随访 5 0例 ,死亡 36例 ,平均存活期 12 0个月 ;生存 14例 ,已平均存活 9 5个月。X刀术后颅外病变稳定者生存期比颅外病变活跃者长。对部分患者应配合全脑放疗。结论 :该技术治疗脑转移瘤近期效果较为满意 ,是一种安全有效的方法。
Objective: To summarize the clinical effect of X knife treatment of brain metastases. Methods: Fifty-eight patients with brain metastases were treated with X knife. A total of 78 lesions were obtained. The average dose of the tumor around the tumor was 19 73 Gy. The tumor was generally covered by 70% ~ 100% isodose lines, and 28 patients received whole-brain radiotherapy. Results: All cases were followed up for 3 ~ 26 months. CT and MRI were followed up in 47 cases. Twenty (42.6%) cases of complete disappearance (CR) and 8 cases (17.0%) of most disappeared (PR) There were 8 cases (17 0%) of disappearance (MR), 6 cases (12 8%) of no change (NC) and 5 cases (106%) of PG. Clinical follow-up 50 cases, 36 deaths, the average survival of 120 months; 14 cases of survival, the average survival of 95 months. X-knife surgery extracranial lesions stable life than extracranial lesions were longer. Part of the patients should cooperate with whole brain radiotherapy. Conclusion: This technique is relatively safe and effective in the treatment of brain metastases.