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应激性溃疡(stress ulcer,SU)是在强烈应激状态下,人体胃及十二指肠出现的急性粘膜糜烂及溃疡等急性病理反应~([1])。作为临床常见急危重症,其应急源包括大面积烧伤、休克、脑出血、颅脑损伤、外科大手术以及大剂量用皮质激素或消炎痛等药物~([2])。该病的主要临床表现为腹部疼痛、呕血及排柏油样大便,严重患者可出现胃出血、胃穿孔等并发症,在带来巨大痛苦的同时严重患者
Stress ulcer (SU) is an acute pathological reaction of acute mucosal erosion and ulcer appearing in the stomach and duodenum in the intense state of stress ([1]). As a common clinical critically ill, its emergency sources include extensive burns, shock, cerebral hemorrhage, head injury, major surgery and large doses of corticosteroids or indomethacin and other drugs ~ ([2]). The main clinical manifestations of the disease are abdominal pain, hematemesis and asphaltic stools, severe cases of gastric bleeding may occur, complications such as gastric perforation, in the same time bring great pain in patients with severe