癫性发作在肾功能衰竭患者中时有发生,是肾功能衰竭患者死亡的重要原因之一。电解质代谢紊乱、酸碱平衡失调、高血压、氮质血症和药代动力学的改变是肾功能衰竭患者更易于出现癫性发作的主要原因。认识并纠正肾功能衰竭患者的病理生理状态是防治癫性发作的有效方式。 Epileptic seizures occur in patients with renal failure from time to time, is one of the important causes of death in patients with renal failure. Electrolytic metabolic disorders, acid-base balance disorders, hypertension, azotemia and pharmacokinetic changes in patients with renal failure are more likely to cause epileptic seizures the main reason. Recognizing and correcting the pathophysiological status of patients with renal failure is an effective way to prevent and treat epileptic seizures.