目的总结十年来结核性脑膜炎患者的治疗情况,进一步提高诊疗水平。方法对1998～2008年本所收治的65例结核性脑膜炎(简称结脑)病例进行分析。结果结脑患者占总住院人的2.8%,其发病年龄14～35岁占50.8%,出现症状至就诊时间平均为28d;合并脑外结核占55.4%,结脑症状明显的平均占85.8%,伴有意识障碍及神经症状的占86.2%;高颅压占73.8%,脑脊液检查符合结脑阳性反应的平均占86.3%;经抗结核、降颅压、激素、脑细胞活化剂等综合治疗,好转出院的占89.2%,病情恶化死亡占6.2%。结论结脑的预后取决于抗结核治疗的早晚,以及开始治疗的正确与否。因此,更加提高早期的诊疗水平,才能有效地控制病死率和致残率的发生。 Objective To summarize the treatment of tuberculous meningitis in the past ten years and to further improve the diagnosis and treatment. Methods A total of 65 cases of tuberculous meningitis (referred to as tuberculous meningitis) admitted to our hospital from 1998 to 2008 were analyzed. Results The patients with tuberculous meningitis accounted for 2.8% of the total inpatients. The age of onset was 50.8% between the ages of 14 and 35, and the average time from symptom onset to treatment was 28 days. The prevalence of tuberculous meningitis accounted for 55.4%, and the average incidence of tuberculous meningitis was 85.8% 86.2% were accompanied by disturbance of consciousness and neurosis; 73.8% were treated with high intracranial pressure; 86.3% were confirmed by cerebrospinal fluid examination in response to tuberculous meningitis; combined treatment of anti-TB, intracranial pressure, hormone and brain cell activator improved 89.2% were discharged from hospital and 6.2% were exacerbated. Conclusion The prognosis of tuberculosis depends on the sooner or later antituberculosis treatment and the correctness of treatment. Therefore, to raise the level of early diagnosis and treatment in order to effectively control the incidence of mortality and morbidity.