80只 Wistar 大鼠经乌拉坦麻醉,以特制的中空双极同心圆电级从第Ⅳ脑室底垂直向延髓腹面探查延髓腹面的血压反应点,并用选择性神经元兴奋剂L-谷氨酸检验。经环枕膜切口向蛛网膜下腔内插入PE-10导管6.0～6.5cm,使其尾端位于脊髓 T_8～T_(10)节段水平,以备蛛网膜下腔给药。改变 T_8～T_(10)节段SPN 的细胞外环境,记录平均动脉压(MAP)、心率 Totally 80 Wistar rats were anesthetized with urethane and the ventricular pressure responses of the medulla oblongata were probed vertically from the bottom of IV ventricle with a special hollow bipolar concentric voltage level. . The PE-10 catheter 6.0 ~ 6.5cm was inserted into the subarachnoid space through the ring of the occipital membrane to make the tail end located at the level of T_8 ~ T_ (10) spinal cord for subarachnoid administration. Changes in the extracellular environment of T_8 ~ T_ (10) SPN segment, recording mean arterial pressure (MAP), heart rate