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目的分析2012年沧州市手足口病(hand-foot-mouth disease,HFMD)的发病情况,为今后沧州市HFMD疫情的防控提供参考。方法收集沧州市2012年HFMD疫情报告的流行病学资料及实验室核酸检测资料,对2012年沧州市HFMD发病情况进行分析。结果 2012年沧州市HFMD病例累计报告12 659例,比上年同期(14 858例)降低14.80%;5月份为发病的高峰期;疫情主要集中在任丘市、肃宁县、沧县、青县、河间市;1岁儿童发病率最高(34.84%);男女发病比例为1.9∶1;病例多发于5岁以下散居儿童(87.51%);实验室病原学检测739份标本,检出EV71型187份(25.30%),CoxA16型263份(35.59%),其他肠道通用病毒感染106份(14.34%);2012年核酸检测总阳性率和EV71阳性率明显低于2011年(P<0.01),CoxA16阳性率明显高于2011年;重症20例,死亡0例。结论沧州市2012年HFMD感染以CoxA16型病毒为主,提示今后沧州市HFMD的疫情应侧重CoxA16型病毒的防控。
Objective To analyze the incidence of hand-foot-mouth disease (HFMD) in Cangzhou in 2012 and provide reference for the prevention and control of HFMD in Cangzhou. Methods The epidemiological data of HFMD epidemic in 2012 and laboratory nucleic acid test data were collected from Cangzhou City in 2012 to analyze the incidence of HFMD in Cangzhou City in 2012. Results A total of 12 659 HFMD cases were reported in Cangzhou City in 2012, down 14.88% from the same period of last year (14 858 cases); the peak was in May; the outbreaks were mainly in Renqiu City, Suning County, Cangxian County, Qingxian County, Hejian City; 1-year-old children the highest incidence (34.84%); male to female incidence ratio was 1.9: 1; cases were more common in children under 5 years of age scattered (87.51%); laboratory etiology 739 specimens detected EV71 187 (25.30%), 263 (35.59%) of CoxA16 and 106 (14.34%) of other enteric virus infections. The positive rate of total nucleic acid and the positive rate of EV71 in 2012 were significantly lower than those in 2011 (P <0.01) CoxA16 positive rate was significantly higher than in 2011; severe cases in 20 cases, 0 cases of death. Conclusion In 2012, CoxA16 infection was the main cause of HFMD in Cangzhou City, suggesting that CoxA16 should be the focus of prevention and control of HFMD in Cangzhou.