论文部分内容阅读
这篇法国专利介绍的是四环素通过溴化方法以合成其衍生物及同系物。四环素和土霉素在惰性溶剂中进行卤代反应,得到11α-卤代-6,12半缩酮化合物,如下式:
This French patent describes the tetracycline method of bromination to synthesize its derivatives and homologs. Tetracycline and oxytetracycline are halogenated in an inert solvent to give 11α-halo-6,12 hemiketal compounds of the formula: