鏈霉素和双氢鏈霉素对于第八对顱神經的特殊毒性是大家知道的,所以有些科学家企图将鏈霉素或双氢链霉素同別的药物結合作成新的制剂以期减少毒性,本文作者所选择的四种鏈霉素新制剂,双氢鏈霉素泛酸盐、双氢鏈霉素对氨基柳酸盐、双氢鏈霉素抗坏血酸盐及链霉素异菸肼衍生物盐就是根据这样的設想而制成的。在本文中作者报道了对这四种新的鏈霉素制剂以及鏈霉素硫酸盐和双氢鎚霉素硫酸盐所进行药理试驗的結果并分別測定了这六种鏈霉素制剂在动物体內的耐药量和半致死量,鑑定了它們的熱原性、对血的 Streptomycin and dihydrostreptomycin for the eighth pair of cranial nerves of the special toxicity is known, so some scientists attempted to streptomycin or dihydrostreptomycin combined with other drugs made into a new preparation in order to reduce toxicity, The authors selected four new streptomycin formulations, dihydrostrepton pantothenate, dihydrostreptomycin, salicylalanine, dihydrostreptomycin ascorbate and streptomycin isoniazid derivative salt It is based on such a vision and made. In this paper, the authors reported the results of pharmacological tests on these four new streptomycin preparations, as well as streptomycin sulphate and diahitramycin sulphate, and determined the effects of the six streptomycin preparations on animals In vivo drug resistance and LD50, identified their pyrogenicity, on the blood