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目的:比较罗格列酮钠片与二甲双胍片分别联合胰岛素治疗2型糖尿病的疗效和安全性。方法:40例单用胰岛素控制血糖不理想的2型糖尿病患者,随机分为A组,太罗组(罗格列酮钠片)(21例);B组,二甲双胍组(19例),进行为期16周的对照观察。结果:两组治疗后空腹及餐后2小时血糖及糖化血红蛋白(HbA1c)均呈有意义的下降(P<0.05),从下降幅度的百分率统计,太罗组下降幅度明显高于二甲双胍组。结论:太罗联合胰岛素治疗对于血糖的控制明显优于二甲双胍联合胰岛素治疗。
Objective: To compare the efficacy and safety of rosiglitazone sodium tablets and metformin tablets combined with insulin in the treatment of type 2 diabetes mellitus. Methods: Forty patients with type 2 diabetes who did not control their blood glucose with insulin alone were randomly divided into two groups: group A, rosiglitazone sodium (21 cases), group B, metformin (n = 19) A 16-week controlled observation. Results: Both fasting and postprandial blood glucose and HbA1c decreased significantly after treatment (P <0.05). According to the percentages of decrease, the declines in Tai Luo group were significantly higher than those in metformin group. CONCLUSION: The control of blood glucose by TRO combined with insulin therapy is superior to metformin and insulin therapy.