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要改善肺癌疗效,必须早期发现。中央型肺癌早期大部分病例能通过纤维光束支气管镜检(FOB)定位和确诊,但在有些病例中如胸片阴性而痰检阳性的隐匿性肺癌或支气管壁伴有慢性炎性病变时,定位就很困难。近年来,日本东京医科大学应用血卟啉衍生物(Hematoporphyrin derivative,HPD)一紫激光发生荧光对早期中央型肺癌定位,并利用红激光的细胞杀伤作用行光照射治疗(Photoradiation treatment,PRT)。
To improve the efficacy of lung cancer, it must be discovered early. Most of early cases of central lung cancer can be identified and diagnosed by fiberoptic bronchoscopy (FOB), but in some cases, such as thoracic epithelial and sputum-positive occult lung cancer or bronchial wall associated with chronic inflammatory lesions, positioning It is very difficult. In recent years, Tokyo Medical University applied Hematoporphyrin Derivative (HPD) to generate fluorescent light for localization of early central lung cancer and photoradiation treatment (PRT) using red laser cell killing.