To the editor:Aggressive angiomyxoma (AA) is a very rare soft tissue tumor which affects mainly the soft tissues of the pelvis and perineum in women.As a slow-growing mesenchymal neoplasm,AA tends to infiltrate locally and recur) Here we reported a case of AA of the vagina.The patient was a 36-year-old woman,who presented with a 10 cm×5 cm×5 cm myxoid,well-circumscribed,rubbery mass arising within the vaginal wall and extending to the perineum.Besides a routine clinical work-up,further examinations including ultrasonography and computed tomography (CT) were performed before the operation to evaluate the extent of the disease and reveal the location,relationship and degree of infiltration between tumor and pelvic organs.