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目的比较米索前列醇舌下含服和常规方法治疗产后出血的临床疗效。方法选取2012年10月—2013年10月平顶山市郏县人民医院收治的足月妊娠产妇112例,随机分为治疗组与对照组,各56例。对照组产妇予以常规方法治疗,治疗组产妇予以舌下含服米索前列醇治疗。观察两组产妇产后出血情况(产后2、24h出血量、产后出血发生率)、第三产程时间、治疗前后血压及心率。结果治疗组产妇产后2、24h出血量少于对照组,产后出血发生率低于对照组,第三产程时间短于对照组,差异有统计学意义(P<0.05);治疗前后两组产妇舒张压、收缩压及心率比较,差异无统计学意义(P>0.05)。结论米索前列醇舌下含服治疗产后出血的临床效果显著,可减少产后出血量,缩短第三产程时间,且安全可靠。
Objective To compare the clinical efficacy of misoprostol sublingual administration and conventional treatment of postpartum hemorrhage. Methods One hundred and twelve full-term pregnant women who were admitted to Juxian People’s Hospital of Pingdingshan from October 2012 to October 2013 were randomly divided into treatment group and control group, with 56 cases in each group. The control group maternal to be treated by conventional methods, the treatment group maternal sublingual misoprostol treatment. Postpartum hemorrhage (postpartum hemorrhage, postpartum hemorrhage rate, postpartum hemorrhage rate), duration of the third stage of labor, blood pressure and heart rate before and after treatment were observed. Results The bleeding rate of postpartum patients in treatment group was less than that in control group at 2 and 24 hours, and the incidence of postpartum hemorrhage was lower than that in control group. The duration of the third stage of labor was shorter than that in control group (P <0.05). Before and after treatment, Pressure, systolic blood pressure and heart rate, the difference was not statistically significant (P> 0.05). Conclusion Misoprostol sublingual treatment of postpartum hemorrhage clinical results were significant, can reduce the amount of postpartum hemorrhage, shorten the duration of the third stage of labor, and safe and reliable.