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目的调查新兵长途徒步行军的肌肉损伤情况及维生素E对肌肉损伤的防护作用。方法选取50名男性新兵随机分为A、B、C、D、E组,每组10名。A、B、C组每天服用不同剂量的维生素E,D、E组口服等剂量的橄榄油,7 d后A～D组徒步行军,E组未徒步行军。徒步行军5 h后抽取静脉血测定其血清肌酸激酶(CK)与乳酸脱氢酶(LDH)活性。结果 CK与LDH活性E组明显低于其他4组(P<0.01),A、B、C 3组活性逐渐降低,且明显低于D组(P<0.01)。A组高于B、C组(P<0.01),但B、C两组间CK差异无统计学意义(P>0.05)。结论维生素E能保护长时间运动所导致的肌肉损伤。
Objective To investigate the muscular injury of recruits long-distance trekkers and the protective effect of vitamin E on muscle damage. Methods Fifty male recruits were randomly divided into A, B, C, D and E groups, with 10 in each group. Groups A, B and C took different daily dose of vitamin E, D and E groups. The rats in groups A and D walked march on foot 7 days later. Group E did not walk on foot. Blood samples were collected for venous blood 5 h after the march to measure the activity of serum creatine kinase (CK) and lactate dehydrogenase (LDH). Results The activities of CK and LDH in E group were significantly lower than those in the other 4 groups (P <0.01). The activities of A, B and C 3 groups decreased gradually and were significantly lower than those in D group (P <0.01). Group A was higher than group B and C (P <0.01), but there was no significant difference between group B and C (P> 0.05). Conclusion Vitamin E can protect muscles from prolonged exercise.