Macrophage-derived matrix metalloproteinase-1 enhances aortic aneurysm formation in transgenic rabbi

来源 :生物医学研究杂志:英文版 | 被引量 : 0次 | 上传用户：mjc198603

【摘要】

：

Increased expression of matrix metalloproteinase-1(MMP-1)has been observed in the lesions of atherosclerosis and aneurysms;however,it is not fully understood wh

【作者】

：

Manabu Niimi Kazutoshi Nishiji

【机构】

：

DepartmentofMolecularPathology,AnimalResearchLaboratory,AnalyticalResearchCenterforExperimentalScien

【出处】

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生物医学研究杂志:英文版

【发表日期】

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2019年4期

【关键词】

：

matrix metalloproteinase-1 MACROPHAGE ATHEROSCLEROSIS ANEURYSM TRANSGENIC rabbit

【基金项目】

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supported in part by research grants from JSPS KAKENHI(JP26460486 to MN and JP15H04718 to JF),NIH grants(R01HL117491and RO1HL129778 to YEC).

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Increased expression of matrix metalloproteinase-1(MMP-1)has been observed in the lesions of atherosclerosis and aneurysms;however,it is not fully understood whether macrophage-derived MMP-1 affects these diseases.To investigate whether macrophage-derived

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Macrophage-derived matrix metalloproteinase-1 enhances aortic aneurysm formation in transgenic rabbi

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