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目的调查铜绿假单胞菌(PAE)临床分布的特点及耐药性,为临床合理选用抗菌药物提供参考。方法收集2010年1月-2014年12月住院及门诊患者标本中分离出的PAE 368株进行统计分析,并测定常用药物的抗药性。结果其中222株PAE来自ICU,占60.3%。368株PAE主要分离自痰液,占76.4%(281/368)。PAE对多数药物的耐药率较高。结论临床分离的PAE主要来源于呼吸道,而且耐药性较严重,应加强细菌培养和药敏监测,合理使用抗生素,预防PAE的医院感染。
Objective To investigate the clinical characteristics and drug resistance of Pseudomonas aeruginosa (PAE) and provide a reference for rational use of antimicrobial agents in clinic. Methods PAE 368 strains isolated from inpatients and outpatients from January 2010 to December 2014 were collected for statistical analysis and drug resistance of commonly used drugs was determined. Among them, 222 PAEs were from ICU, accounting for 60.3%. 368 strains of PAE were mainly isolated from sputum, accounting for 76.4% (281/368). PAE is resistant to most drugs. Conclusions The clinical isolates of PAE mainly come from the respiratory tract, and the drug resistance is more serious. Bacterial culture and drug susceptibility monitoring should be strengthened. Rational antibiotics should be used to prevent nosocomial infections of PAE.