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目的 探讨窒息对新生儿胃排空功能的影响。方法 采用B型实时超声显像法观察 32例窒息新生儿餐后胃窦纵切面积的动态变化 ,并检测餐前及餐后半小时血中胃动素、一氧化氮 (NO)水平 ,同时与 10例正常新生儿比较。结果 与正常组相比 ,轻度窒息组 10 %、5 0 %、10 0 %胃排空时间及餐前、餐后胃动素、NO水平无明显变化 ,差异无显著性意义 (均为P >0 0 5 ) ,而重度窒息组胃排空时间明显延长 ,餐前、餐后胃动素、NO水平明显升高 ,差异有极显著意义 (均为P <0 0 1)。结论 重度窒息新生儿胃排空延迟 ,与胃动素、NO的变化有关。
Objective To investigate the effect of asphyxia on neonatal gastric emptying function. Methods The dynamic changes of longitudinal section area of antral gastrocnemius in 32 neonates with asphyxia were observed by real-time ultrasound B method. The levels of motilin and nitric oxide (NO) in blood were measured before and after the meal for half an hour. Compared with 10 normal newborns. Results Compared with the normal group, 10%, 50%, 100% gastric emptying time and the levels of motilin and NO before and after meal in mild asphyxia group had no significant difference (all P > 0 0 5). However, the time of gastric emptying in severe asphyxia group was significantly prolonged, and the levels of motilin and nitric oxide were significantly increased after meals (P <0.01). Conclusion Severe asphyxia neonatal delayed gastric emptying, and motilin, NO changes.