激素发挥作用的第一步是和靶细胞的受体结合,因此,激素受体的数量,它和激素结合的亲和力的大小,以及结合后能否正常地发挥效应,均是靶细胞对激素反应性的重要环节。近年来对激素受体的研究证明,有许多疾患其靶细胞的敏感性改变在于受体的变化,这种情况称为“受体病(receptor disease)”。本文对激素受体病和受体异常作一概述,大致可分为下列5种情况。遗传性疾病伴激素受体减少或缺乏。睾丸女性化综合征为伴 X 染色体的隐性 The first step in the role of hormones and target cell receptor binding, therefore, the number of hormone receptors, the size of its affinity and hormone binding, as well as the normal effect after binding, are target cells on the hormone response An important part of sex. In recent years, studies on hormone receptors have demonstrated that there are many diseases in which the sensitivity of target cells changes in response to receptors, a condition called “receptor disease.” This article on hormone receptor disease and receptor abnormalities made an overview, can be divided into the following five cases. Hereditary diseases with reduced or lack of hormone receptors. Testicular feminization syndrome with recessive X chromosome