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过去对前列腺素F_2α的降压作用研究不多,结果也互有矛盾。作者用96只200～250克的白鼠进行实验。按常用法描记颈总动脉的平均血压。在分别注射血管紧张素(0.5和1毫克/公斤)和肾上腺索(0.5和1毫克/公斤)前后,由股静脉注入不同剂量的PGF_2α,以观察PGF_2α对动脉血压和上述二种药物加压效应的影响。结果如次: 1.小剂量PGF_2α(2毫克/公斤)可引起短暂降
In the past, there was not much research on the antihypertensive effect of prostaglandin F_2α, and the results contradict each other. The author used 96 200 ~ 250 grams of rats for experiments. According to common carotid artery average blood pressure. Different doses of PGF 2α were injected into femoral vein before and after injection of angiotensin (0.5 and 1 mg / kg) and adrenal cord (0.5 and 1 mg / kg) respectively to observe the effect of PGF 2α on arterial blood pressure and the above two drugs Impact. The results are as follows: 1. Small doses of PGF 2α (2 mg / kg) can cause transient drop