以巨核细胞病态生成为主要特征的MDS一例报告

来源 :浙江医科大学学报 | 被引量 : 0次 | 上传用户:milamiya2009
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1 病例摘要患者男,28岁,农民,住院号160390.自1980年起自感头昏乏力、食欲减低和失眠.1983年起上述症状加重,去当地医院检查:Hb 40g/L,WBC3×10~9/L,血小板6.1×10~9/L,骨髓检查呈增生性骨髓象,诊为重度贫血原因待查,住入当地医院,经输血输液等治疗,症状稍有改善后出院.1984年2月病情加重,于同年4月4日住入我院.体检:贫血貌,消瘦,浅表淋巴结未及;血压20.0/14.7kPa,心率100,律齐,肺无殊;腹软无压痛,肝肋下1.0cm,脾未及.实验室检查:Hb32k/l,WBC2.9×10~9/L,中性0.66、淋巴0.33、嗜酸0.10,未见幼稚细胞,血小板10.6×10~9/L,网织红细胞0.011,尿常规阴性,尿胆原不增加,尿胆素(+),红细胞渗透脆性试验:开始溶血0.44%、完全溶血0.30%,血沉60mm/h, 1 Case Summary Patient male, 28 years old, resident, hospital number 160390. Self-aggravated fatigue, loss of appetite and insomnia since 1980. The above symptoms were aggravated by 1983 and went to the local hospital for examination: Hb 40 g / L, WBC 3 × 10 ~ 9 / L, platelets 6.1 × 10 ~ 9 / L, bone marrow examination was hyperplastic bone marrow, diagnosed as severe anemia to be investigated, admitted to the local hospital, transfusion and other treatment, the symptoms were slightly improved after discharge. In February the condition worsened, in our hospital on April 4, the same year.Physiological examination: anemia appearance, weight loss, superficial lymph nodes was less than; blood pressure 20.0 / 14.7kPa, heart rate 100, law Qi, lung no special; 1.0cm in liver, 1.0cm in spleen and less in spleen.Laboratory examination: Hb32k / l, WBC 2.9 × 10 ~ 9 / L, Neutral 0.66, Lymph 0.33, Eosinophil 0.10, no naive cells, platelets 10.6 × 10 ~ 9 / L, reticulocyte 0.011, urine routine negative, urobilinogen is not increased, urobilinogen (+), erythrocyte infiltration fragility test: hemolysis 0.44%, complete hemolysis 0.30%, erythrocyte sedimentation rate 60mm / h,
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