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目的探讨肠淋巴液对失血性休克的抗休克作用与肾上腺素能α受体的关系。方法45只失血性休克大鼠分为三组 :酚苄明(POB)组、单纯淋巴液治疗组及生理盐水对照组。POB组放血后以POB阻断α -肾上腺素能受体。前2组给予小量肠淋巴液及输血后观察存活时间及血压 ,对照组以生理盐水代替肠淋巴液。结果POB组与单纯淋巴液治疗组比较的存活率分别为53.33%和46.67% ,均显著高于生理盐水对照组(P<0.05) ,但POB组的血压显著低于单纯淋巴液治疗组(P<0.05) ,与生理盐水对照组无显著性差异(P>0.05)。结论淋巴液的抗休克作用可能不是通过肾上腺素能α受体发挥作用的
Objective To investigate the anti-shock effect of intestinal lymph on hemorrhagic shock with adrenergic receptor α. Methods Forty-five hemorrhagic shock rats were divided into three groups: PGE group, simple lymphatic fluid group and saline control group. The POB group blocks alpha-adrenergic receptors with POB after exsanguination. The first two groups were given a small amount of intestinal lymph and blood transfusion after the observation of survival time and blood pressure, the control group instead of intestinal lymph glands with saline. Results The survival rates of POB group and pure lymphatic fluid group were 53.33% and 46.67%, respectively, which were significantly higher than those of saline control group (P <0.05). However, the blood pressure of POB group was significantly lower than that of simple lymphatic fluid treatment group (P <0.05), no significant difference with the saline control group (P> 0.05). Conclusion The anti-shock effect of lymphatic fluid may not play a role through the adrenergic α receptor