抗菌素在临床使用中的过敏反应及毒性反应有时不能及时发现,尤其是抗菌素过敏引起的发热反应。现将我所观察到的2例报告如下。 例1:聂××,女,12岁。患者家属自述5天前因感冒、咳嗽、发热,在家由村医每天肌注青霉素治疗,2天后患儿发烧更甚,来我所诊治。体检检查未见明显异常,体温39.1℃。住院医师继续每日以400万单位青霉素静脉点滴,二天后。患者皮肤出现散在斑丘疹,咳嗽减轻,但持续高热。经内儿科医师会诊考虑为青 Antibiotics in clinical use of allergic reactions and toxic reactions sometimes can not be found in time, especially fever caused by antibiotic allergies. Now I observed 2 cases reported as follows. Example 1: Nie × ×, female, 12 years old. The patient’s family readme 5 days ago because of a cold, cough, fever, at home by the village doctors daily penicillin treatment, fever in children even more after 2 days, come to my diagnosis and treatment. Physical examination showed no significant abnormalities, body temperature 39.1 ℃. Residents continue to daily intravenous penicillin 4 million units, two days later. Patients with scattered rash on the skin, cough to reduce, but continued high fever. Consultation by the pediatrician considered green