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人的T细胞是表达MHCⅡ类分子抗原和抗原递呈细胞(APCs)特有的粘附分子。最近体内体外实验证明,T细胞具有抗原递呈功能。通过在已经被活化的T细胞中诱导免疫无能(anergy)及在静止的T细胞中诱导细胞毒作用,T细胞对免疫应答提供下调的信号。WernerJP和他的同事们指出:“这代表T细胞的主要阴性机制”。
Human T cells are specific molecules that express MHC class II antigen and antigen-presenting cells (APCs). Recent in vitro and in vivo experiments show that T cells have antigen presenting function. T cells provide a down-regulated signal to an immune response by inducing anergy in already activated T cells and inducing cytotoxic effects in resting T cells. WernerJP and colleagues point out: “This represents the major negative mechanism of T cells.”