多数细菌的鞭毛是由单一多肽组成的多聚体，但与此相反，梅毒螺旋体 (TP)的内鞭毛不在菌体表面，是由多肽排列于外鞘和中央核内， TP鞭毛的特殊解剖位置，使其不应是完整菌体最先识别的抗原，而事实则相反，鞭毛蛋白是人类感染 TP后最先产生 IgM和 IgG抗体的抗原，可能是因其可 Most bacterial flagella are composed of a single polypeptide multimers, but in contrast, the internal flagella of Treponema pallidum (TP) is not on the surface of the cell, is arranged in the outer sheath and the central nucleus of the polypeptide, TP flagella special anatomical location , So that it should not be the first antigen recognized by intact bacteria, but the fact is that flagellin is the first antigen that produces IgM and IgG antibodies after human infection of TP, probably because of