Synthesis and Biological Evaluation of Pyranone Analogues of Territrem B

来源 :中国化学快报（英文版） | 被引量 : 0次 | 上传用户：tk6014

【摘要】

：

23 compounds containing pyranone pharmaeophore of territrem B were designed and synthesized. Some of the analogues showed IC50 values of AChE inhibition at 10-5

【作者】

：

Xiang Rui JIANG Lei AO Chang X

【机构】

：

Department of Traditional Chinese Medicine and Natural Drug Research,Zhejiang Hisun Naturelite Pharm

【出处】

：

中国化学快报（英文版）

【发表日期】

：

2004年期

【关键词】

：

2H-Pyran-2-one territrim B synthesis AChE inhibitor

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23 compounds containing pyranone pharmaeophore of territrem B were designed and synthesized. Some of the analogues showed IC50 values of AChE inhibition at 10-5 mol/L.

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Synthesis and Biological Evaluation of Pyranone Analogues of Territrem B

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