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目的:探讨使用埃索美拉唑联合莫沙必利治疗反流性食管炎的效果。方法:选取近几年我院收治的60例反流性食管炎患者作为研究对象。随机将这些患者分为奥美拉唑组和埃索美拉唑组。为奥美拉唑组患者使用奥美拉唑联合莫沙必利进行治疗,为埃索美拉唑组患者使用埃索美拉唑联合莫沙必利进行治疗。然后比较两组患者临床症状改善的情况及其进行内镜检查的结果。结果 :经治疗,埃索美拉唑组患者临床症状改善的总有效率及经内镜检查显示其改善的总有效率均明显高于奥美拉唑组患者,差异具有统计学意义(P<0.05)。治疗期间,两组患者均未出现影响治疗的不良反应。结论 :使用埃索美拉唑联合莫沙必利治疗反流性食管炎的效果显著,安全性高。
Objective: To investigate the effect of esomeprazole combined with mosapride on reflux esophagitis. Methods: Sixty patients with reflux esophagitis admitted in our hospital in recent years were selected as the research object. These patients were randomly divided into omeprazole group and esomeprazole group. Omeprazole group with omeprazole combined with mosapride treatment for esomeprazole patients with esomeprazole combined with mosapride treatment. Then compare the clinical symptoms of two groups of patients to improve the situation and the results of endoscopic examination. Results: After the treatment, the total effective rate of improving clinical symptoms and the total effective rate of endoscopic examination in esomeprazole group were significantly higher than those in omeprazole group (P < 0.05). During the treatment, no adverse reactions affecting the treatment occurred in both groups. Conclusion: The effect of esomeprazole combined with mosapride on reflux esophagitis is significant and safe.