干燥裙带菜(Undaria pinnatifida)孢子叶(10kg),以15℃自来水清洗10min后碾碎,用乙醇80℃回流提取2h,过滤得到脱脂藻。脱脂藻(3kg)经0.15N盐酸提取,提取液离心、过滤。提取物用3N氢氧化钠调至中性,然后超滤。浓缩后,加入4倍体积乙醇,过筛(300目),干燥后得到粗岩藻依聚糖(52g)。 The Undaria pinnatifida spores (10 kg) were dried, washed with tap water at 15° C. for 10 min, ground, extracted with ethanol at 80° C. for 2 h, and filtered to obtain defatted algae. The defatted algae (3 kg) was extracted with 0.15 N hydrochloric acid and the extract was centrifuged and filtered. The extract was made neutral with 3N sodium hydroxide and then ultrafiltered. After concentration, 4 volumes of ethanol were added, sieved (300 mesh) and dried to give crude fucoidan (52 g).