新生儿缺氧缺血性脑病是新生儿窒息后的严重并发症,病情重,病死率高,中、重度者可伴有中枢性呼吸衰竭,所以积极治疗呼吸衰竭是抢救新生儿生命的关键所在。我们于2001年12月-2003年12月,用纳洛酮治疗新生儿缺氧缺血性脑病并中枢性呼衰50例,临床疗效满意,现报告如下。1资料与方法1.1病例选择　按入院先后顺序随机分为二组,治疗组和对照组各50例。胎龄37-41+2周,体重2.5-3.8kg。二 Neonatal hypoxic-ischemic encephalopathy is a serious complication after neonatal asphyxia, severe illness, high mortality, moderate and severe may be associated with central respiratory failure, so active treatment of respiratory failure is the key to rescue the life of newborn . We December 2001 - December 2003, naloxone treatment of neonatal hypoxic-ischemic encephalopathy and central respiratory failure 50 cases, the clinical efficacy is satisfactory, are as follows. 1 Materials and Methods 1.1 Case Selection According to the order of admission were randomly divided into two groups, the treatment group and the control group of 50 cases. 37-41 + 2 weeks gestational age, weight 2.5-3.8kg. two