很多文献报告了金属离子和抗菌素的作用关系,某些金属离子能减少甚至使某些抗菌素的作用丧失,而有些抗菌素则可被金属离子增强。本文对去甲基氯四圜素作了进一步的研究,实验结果表明,金属离子亚铁,铜、镍、镁等都可使去甲基氯四圜素的抗菌作用降低,而只有硫酸锌不同,它却能增强去甲基氯四圜素的抗菌作用,实验表明,当在浓度很低以致在 Many papers report the interaction between metal ions and antibiotics. Some metal ions can reduce or even eliminate the action of some antibiotics. Some antibiotics can be enhanced by metal ions. In this paper, the further study on demethylchlorosilane has been carried out. The experimental results show that the antibacterial effect of demethylchlorosilane can be reduced by ferrous metals such as ferrous, copper, nickel and magnesium, while only zinc sulfate is different , But it can enhance the antimicrobial effect of desmethylchloro-tetracycline, experiments show that when the concentration is so low that at