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在正常妇女的黄体中期经鼻给大剂量的 LH-RH 促效剂 Buserelin,孕酮(P)及雌二醇(E_2)在血中的水平降低,黄体期缩短1～4天。本文报告33例志愿者,平均年龄为30.7±1(19～40岁),月经均正常,至少有2个月以上的 BBT 测定,没有内分泌的异常,各项生化测定正常,在六个月内未服避孕片或其他激素类药物。志愿者必须住院,以便测得内分泌快速的变化,从 LH 高峰后的第1至第10天,每天给药2个剂量各为300μg,时间分别为上午8时及下午6时。在月经中期的第1及第2天,给第一个剂量2小时后,LH 受刺激的幅度最
In normal mid-corpus luteum, large doses of LH-RH agonist Buserelin, progesterone (P) and estradiol (E_2) were reduced in the blood and the luteal phase shortened by 1 to 4 days. This article reports 33 volunteers, the average age of 30.7 ± 1 (19 to 40 years), normal menstruation, BBT at least 2 months or more, no endocrine abnormalities, the biochemical determination of normal within six months Did not take birth control pills or other hormonal drugs. Volunteers must be hospitalized in order to measure rapid changes in endocrinology. Two doses of 300 μg administered daily from day 1 to day 10 after LH peak are observed at 8 am and 6 pm, respectively. On the first and second days of the mid-menstrual period, the first dose of 2 hours after the LH stimulated the most