论文部分内容阅读
反复呼吸道感染(RRTI)是儿童的常见疾病,其病因和发病机理复杂。本文测定了40例RRTI 患儿体外淋巴细胞增殖反应及T 细胞分泌的IL-2、BCGFs 和IL-6活性。结果发现RRTI 患儿体外T、B 淋巴细胞增殖功能低下,T 细胞分泌的IL-2、BCGFs 和IL-6活性降低。提示机体免疫功能低下或缺陷是RRTI 发病原因之一,细胞因子活性降低可能具有重要作用.
Recurrent respiratory tract infections (RRTI) is a common childhood disease, its etiology and pathogenesis is complicated. In this study, the proliferative response of lymphocytes and IL-2, BCGFs and IL-6 secreted by T cells in 40 RRTI children were measured. The results showed that children with RRTI had poor T and B lymphocyte proliferation in vitro, and the activity of IL-2, BCGFs and IL-6 secreted by T cells decreased. Suggest that immune dysfunction or defect is one of the causes of RRTI, decreased cytokine activity may play an important role.