由非内分泌肿瘤合成和分泌的ACTH可产生库兴氏综合征的临床改变。此时伴异位性促脂素的分泌。ACTH和促脂素通过共同的前体分子而合成,近来发现阿片样肽类β内啡肽和蛋氨酸脑啡肽均有β促脂素分子C端部份的共同氨基酸序列。作者因此决定研究分泌ACTH的非内分泌肿瘤患者中是否 ACTH synthesised and secreted by non-endocrine tumors can produce clinical changes in Cushing’s syndrome. At this time with the secretion of ectopic lipoprotein. ACTH and lipoitin are synthesized by a common precursor molecule, and it has recently been found that the opioid peptides beta-endorphin and methionine enkephalin both have the common amino acid sequence of the C-terminal part of the beta-lipotropin molecule. The authors therefore decided to investigate whether patients with non-endocrine tumors secreting ACTH are