论文部分内容阅读
黄腐酸是一种水溶性较好,分子量较小的腐植酸。它具有抗肿瘤及免疫兴奋作用,给小鼠经口灌胃~3H-黄腐酸后15分钟,血中即可测到放射性,4小时达高峰,72小时后血中仍可测到少量放射性。腹腔注射~3H-黄腐酸后,肾、肝、血及骨组织中放射性最高,脾、肠、胃、肺、肌、胸腺及脑组织中依次减少;经口灌胃后,放射性在胃、肾、血、肝组织中最高,肠、心、脾、肺、胃、肌、胸腺及脑组织中依次减少。腹腔注射后,24小时内自尿及粪分别外排34.2%及24.2%,口服后分别从尿及粪排泄13%及62%。
Fulvic acid is a water-soluble, smaller molecular weight humic acid. It has anti-tumor and immune excitatory effects, to mice by oral gavage ~ 3H-fulvic acid after 15 minutes, the blood can be measured radioactive, reached the peak at 4 hours, 72 hours after the blood can still be measured a small amount of radioactivity . After intraperitoneal injection of ~ 3H-fulvic acid, the highest radioactivity was found in the kidney, liver, blood and bone tissues, followed by decreasing in the spleen, intestine, stomach, lung, muscle, thymus and brain tissues; Kidney, blood, liver tissue highest, intestine, heart, spleen, lung, stomach, muscle, thymus and brain tissue in turn decreased. After intraperitoneal injection, urine and feces were excreted by 34.2% and 24.2% respectively within 24 hours. After oral administration, urine and feces were excreted by 13% and 62% respectively.