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了解门静脉高压患者胃幽门螺旋杆菌（Ｈ．Ｐｙｌｏｒｉ）感染及意义。方法应用胃镜，胃粘膜组织学检查和ＨＰ培养，调查１３５例门静脉高压患者，对照组为４２例无肝病史的非溃疡性消化不良患者。结果门静脉高压组，伴充血性胃病者６３例，１７例检出ＨＰ感染（２７０）；无充血性胃病者７２例，１８例检出ＨＰ（２５０）。对照组４２例，ＨＰ感染２３例（５５０）。门静脉高压性胃病ＨＰ感染低于对照组，充血性胃病存在及程度与ＨＰ感染无关。结论不应视ＨＰ感染为门静脉高压性胃病的发病原因，对肝硬化无须常规作ＨＰ根除治疗。
To understand the significance of H. pylori infection in patients with portal hypertension. Methods Gastroscopy, gastric mucosa histology and HP culture were used to investigate 135 patients with portal hypertension and 42 patients with non-ulcer dyspepsia without liver disease. Results In the portal hypertension group, there were 63 cases with congestive gastric diseases and 17 cases with HP infection (270 cases). There were 72 cases without congestive gastropathy and 18 cases with HP (250 cases). Control group, 42 cases, HP infection in 23 cases (550). HP infection of portal hypertensive gastropathy was lower than that of control group, and the presence and extent of congestive gastropathy were not related to HP infection. Conclusion HP infection should not be considered as the pathogenesis of portal hypertensive gastropathy, and no need for routine eradication of cirrhosis.