胆脂瘤位于中耳腔，鼓窦至乳突腔由上皮（皮质）及基质（皮质周围）形成口袋状或树技状结构，它表现为在中耳腔进行性生长伴高度角化特性及其周围组织和骨质破坏。角蛋白细胞增生即分化演变的调节机制由钙结合细胞表面分子所参与。钙颗粒素A及B为细胞内钙结合蛋白，经由唾液腺 Cholesteatoma is located in the middle ear cavity, the drum sinus to the mastoid cavity from the epithelium (cortex) and stroma (around the cortex) to form a pocket or tree-like structure, which showed the middle ear cavity with high degree of keratosis and sexual growth characteristics and The surrounding tissue and bone destruction. The regulatory mechanism of keratinocyte proliferation, which is the evolution of differentiation, is involved in the binding of calcium-binding cell surface molecules. Calcium Granules A and B are intracellular calcium-binding proteins via the salivary gland