论文部分内容阅读
目的探讨胰腺原发性平滑肌肉瘤的临床特征、影像学表现、病理形态特点、诊断和鉴别诊断及预后。方法分析1例胰腺原发性平滑肌肉瘤,结合病理形态特点、免疫组化表现及与其他胰腺梭形细胞肿瘤的鉴别诊断,并进行文献复习。结果胰腺原发性平滑肌肉瘤由梭形的平滑肌样细胞构成,在胰腺组织中呈浸润性生长,有坏死,伴有丰富的血管生成。免疫组化:SMA和vimentin(+),calponin(±),ALK、AE1/AE3、CD117和S-100(-)。结论胰腺原发性平滑肌肉瘤是一种胰腺罕见的肉瘤,预后较差,免疫组织化学染色对于明确诊断有重要作用。
Objective To investigate the clinical features, imaging findings, pathological features, diagnosis, differential diagnosis and prognosis of primary pancreatic leiomyosarcoma. Methods One case of primary leiomyosarcoma of the pancreas was analyzed. The pathological features, immunohistochemical findings and differential diagnosis of other pancreatic spindle cell tumors were reviewed and reviewed. Results Primary pancreatic leiomyosarcoma consisted of spindle-shaped smooth muscle-like cells, which showed invasive growth and necrosis in the pancreas with abundant angiogenesis. Immunohistochemistry: SMA and vimentin (+), calponin (±), ALK, AE1 / AE3, CD117 and S-100 (-). Conclusions Primary leiomyosarcoma of the pancreas is a rare sarcoma of the pancreas with poor prognosis. Immunohistochemical staining plays an important role in the diagnosis.