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目的 探讨支气管动脉灌注化疗 (BAI)或合并栓塞 (BAE)对中、晚期肺癌的疗效。方法 对 1 1 0例Ⅱ Ⅳ期肺癌行BAI或合并BAE治疗 ,观察近期疗效及远期随访结果。结果 单纯BAI 70例 ,合并BAE40例。单纯BAI的缓解率为 6 1 4 % ,有效率为 88 6 %。合并BAE的缓解率为72 5 % ,有效率为 95 0 %。两者相比无显著性差异。中央型肺癌的缓解率为 73 4 % ,有效率为95 4 %。周围型肺癌的缓解率为 5 3 3% ,有效率为 84 4 %。两者相比有显著差异。治后生存期平均 1 4 5个月 ,3例生存 5年以上。结论 BAI是中、晚期肺癌安全有效的疗法。
Objective To investigate the effect of bronchial arterial infusion chemotherapy (BAI) or combined embolization (BAE) on middle and late stage lung cancer. Methods One hundred and ten patients with stage IIIV lung cancer were treated with BAI or with BAE. The short-term efficacy and long-term follow-up results were observed. Results There were 70 cases of pure BAI and 40 cases of BAE. The remission rate of pure BAI was 614%, and the effective rate was 88.6%. The remission rate of combined BAE was 72.5% with an effective rate of 95.0%. There was no significant difference between the two. The remission rate of central lung cancer was 73.4%, with an effective rate of 95.4%. The remission rate of peripheral lung cancer was 533%, and the effective rate was 84.4%. There are significant differences between the two. The average survival time after treatment was 145 months, and 3 cases survived for more than 5 years. Conclusion BAI is a safe and effective treatment for lung cancer in middle and late stage.