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目的评价超选择子宫动脉化疗栓塞治疗宫颈癌的临床疗效及其安全性。方法纳入宫颈癌患者58例,随机分为治疗组28例和对照组30例。治疗组予超选择子宫动脉化疗栓塞治疗,对照组予广泛性子宫切除加盆腔淋巴结清扫术,观察并记录其近期疗效和不良反应事件。结果治疗组和对照组近期有效率分别为82.1%和90.0%,差异无统计学意义(P>0.05)。治疗后评估治疗组5例NS患者行手术治疗,对照组3例NS患者后续以放射治疗。两组患者均无严重并发症发生。结论超选择子宫动脉化疗栓塞治疗宫颈癌能减轻患者痛苦,提高患者生存质量,是一种安全有效的治疗方法 。
Objective To evaluate the clinical efficacy and safety of superselective uterine artery chemoembolization in the treatment of cervical cancer. Methods Fifty-eight patients with cervical cancer were randomly divided into treatment group (n = 28) and control group (n = 30). The treatment group was given superselective uterine artery chemoembolization. The control group was treated by extensive hysterectomy and pelvic lymphadenectomy. The curative effect and adverse reaction events were observed and recorded. Results The effective rates of the treatment group and the control group were 82.1% and 90.0% respectively, with no significant difference (P> 0.05). After treatment, 5 NS patients in the treatment group were treated by surgery, and 3 NS patients in the control group were followed up with radiotherapy. No serious complications occurred in both groups. Conclusion Superselective uterine artery chemoembolization in the treatment of cervical cancer can reduce the pain of patients and improve the quality of life of patients. It is a safe and effective treatment.