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目的了解2010年湖北省襄阳市手足口病各主要病原的流行趋势,为制定2011年的手足口病预防控制措施提供实验依据。方法应用荧光RT-PCR对392份手足口病例标本进行检测。结果襄阳市手足口病的发病年龄集中在1～3岁;男童明显多于女童;3-5月,襄阳市有一个手足口病的流行高峰。手足口病的病原体有从CoxA16为主向EV71为主的转变。重症手足口以EV71感染为主。结论 2011年襄阳市的手足口病防控形势严峻,应继续加强监测。
Objective To understand the prevalence trend of major pathogens of hand-foot-mouth disease in Xiangyang City in 2010 and provide experimental evidence for the prevention and control measures of hand-foot-mouth disease in 2011. Methods 392 samples of hand, foot and mouth were detected by fluorescence RT-PCR. Results The incidence of hand-foot-and-mouth disease in Xiangyang was mainly between 1 and 3 years old. There were more boys than girls. From March to May, there was a peak of HFMD in Xiangyang. Hand, foot and mouth disease pathogens from CoxA16-based EV71-based change. Severe hand, foot and mouth to EV71 infection. Conclusion The hand-foot-mouth disease prevention and control in Xiangyang in 2011 is in a severe situation. Monitoring should continue to be strengthened.