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将６１例十二指肠球部溃疡（ＤＵ）患者分成二组，青年组３４例，中老年组２７例。用ＤｉｇｉｔｒｉｐｐｅｒＭＫⅢ型ｐＨ记录仪监测患者治疗前胃内２４ｈｐＨ变化。以ｐＨ＜１、ｐＨ＜２、ｐＨ＜３的总时间百分率，平均ｐＨ和中位ｐＨ为观察指标，并判定有无十二指肠胃反流。结果显示：ｐＨ＜２和ｐＨ＜３的总时间百分率，在青年组显著高于中老年组（Ｐ＜０．０５）。十二指肠胃反流的发生率，青年组３２．４％，中老年组５１．９％。２４ｈｐＨ监测ＤＵ患者显示，高酸分泌确是ＤＵ患者的主要致病因素，其在青年ＤＵ患者中更显重要。而十二指肠胃反流可能在老年患者的发病中起重要作用。因此，在临床治疗中应有所侧重
Sixty-one patients with duodenal ulcer (DU) were divided into two groups: 34 in young group and 27 in middle-aged and elderly group. The changes of 24 h before gastric cancer were monitored by Digitripper MKⅢ pH logger. The total time percentage of pH <1, pH <2, pH <3, mean pH and median pH were observed, and the presence or absence of duodenogastric reflux was determined. The results showed that the total time percentage of pH <2 and pH <3 was significantly higher in young group than in middle-aged group (P <0.05). The incidence of duodenogastric reflux was 32.4% in young group and 51.9% in middle-aged and elderly group. DU patients at 24hpH monitoring show that high acid secretion is indeed a major risk factor for DU patients, which is even more important in young DU patients. Duodenogastric reflux may play an important role in the pathogenesis of elderly patients. Therefore, in clinical treatment should be focused