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[目的]观察复方苦参结肠溶胶囊对溃疡性结肠炎(UC)的治疗作用。[方法]将18例UC患者随机、单盲、阳性平行对照分为复方苦参结肠溶胶囊组(治疗组,11例)和柳氮磺吡啶组(对照组,7例),服药时间均为8周。对比观察2组患者服药前后的症状、体征、大便常规、结肠镜和病理检查,并监测肝肾功能、血尿常规、心电图等变化。[结果]治疗组症状、体征、大便常规、结肠镜和病理检查结果评分均优于对照组(P<0.05)。[结论]复方苦参结肠溶胶囊对UC有较好的治疗作用,且无明显的不良反应,值得临床推广运用。
[Objective] To observe the therapeutic effect of compound kushen colon capsule on ulcerative colitis (UC). [Methods] The randomized, single-blind and positive parallel control of 18 patients with UC were divided into compound kushen colon-colic group (treatment group, 11 cases) and sulfasalazine group (control group, 7 cases) 8 weeks. The symptoms, signs, stool routine, colonoscopy and pathological examination before and after treatment were observed in 2 groups of patients, and the changes of liver and kidney function, hematuria and electrocardiogram were monitored. [Results] The symptoms, signs, stool routine, colonoscopy and pathological examination scores of the treatment group were better than the control group (P <0.05). [Conclusion] Compound kushen colon-colonic capsule has a good therapeutic effect on UC with no obvious adverse reactions, which is worthy of clinical promotion and application.