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低氧（营养液通入９５％Ｎ２＋５％ＣＯ２）可收缩离体猪冠状动脉。氧化氮（ＮＯ）供体ＳＩＮ—１０．１、１和１０μｍｏｌ·Ｌ－１可浓度依赖性地抑制低氧收缩作用。钙通道阻断剂维拉帕米（Ｖｅｒａｐａｍｉｌ）０．１和１μｍｏｌ·Ｌ－１亦可浓度依赖性地抑制低氧收缩离体猪冠脉的作用。
Hypoxia (nutrient solution with 95% N2 + 5% CO2) can contracted isolated porcine coronary arteries. Nitric oxide (NO) donors SIN-10.1, 1 and 10 μmol·L-1 inhibited hypoxia-induced contraction in a concentration-dependent manner. The calcium channel blockers Verapamil 0.1 and 1 μmol·L-1 also inhibited the hypoxia-contracting porcine coronary artery in a concentration-dependent manner.