本文试图从药物的吸收溶散原理，结合工作经验教训．对影响中药丸、片剂崩解因素作一探讨。1药物吸收崩解原理药物崩解机制一般认为主要是膨胀作用与孔隙。毛细管及湿润作用。固体制剂的药物溶出，由其表面湿润过程决定。亲水物质由于吸水后的膨胀性并引起崩解。药物成形后形成 This article attempts to absorb the principle of dissolution of drugs, combined with work experience and lessons learned. Discuss the factors that affect the disintegration of traditional Chinese medicine pills and tablets. 1 drug absorption disintegration principle Drug disintegration mechanism is generally believed to be mainly expansion and porosity. Capillary and wet action. The dissolution of the drug from the solid formulation is determined by the surface wetting process. Hydrophilic substances cause disintegration due to swelling after absorbing water. Formed after drug formation