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一过性脑缺血发作(TIA)或非致残性缺血性脑卒中而未经预防性治疗的患者中,每年血管原性死亡的危险度为7%~12%。众所周知,阿司匹林能使这种危险度降低20%~25%。在发生TIA或非致残性卒中后的患者中,用β受体阻滞剂再次预防性治疗血管意外是一项新的措施。因它能预防心梗后患者的血管意外,并能降低血压,这是脑卒中的主要危险因素。本文目的是评价在TIA或非致残性卒中后的患者中阿替洛尔对血管原性,脑卒中或心梗引起死亡的发生率的影响以及对血压的影响。 对象和方法 在双盲的安慰剂对照试验中,总
In patients who have had a transient ischemic attack (TIA) or non-ischemic stroke but have not been treated prophylactically, the risk of death of the vasogenic agent is between 7% and 12% per year. As we all know, aspirin can reduce the risk of 20% to 25%. In patients with TIA or non-disabling stroke, prophylactic treatment of vascular accident with beta-blocker is a new measure. Because it can prevent vascular accident in patients after myocardial infarction, and can reduce blood pressure, which is the main risk factor for stroke. The purpose of this paper is to evaluate the effect of atenolol on the incidence of vasogenicity, stroke or MI-induced death in patients after TIA or non-disabling stroke and on blood pressure. Subjects and Methods In a double-blind placebo-controlled trial, total