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目的研究泮托拉唑治疗消化性溃疡合并出血的临床效果。方法 100例消化性溃疡合并出血患者,随机分为对照组和观察组,各50例。两组基础治疗情况相同,对照组添加西咪替丁进行静脉滴注治疗,观察组则添加泮托拉唑进行静脉滴注治疗,观察并比较两组疗效。结果对照组总有效率为68.00%,观察组总有效率为92.00%,观察组总有效率明显高于对照组,差异具有统计学意义(P<0.05)。观察组的不良反应总发生率为4.00%,对照组的不良反应总发生率为18.00%,观察组不良反应总发生率明显低于对照组,差异具有统计学意义(P<0.05)。结论泮托拉唑治疗消化性溃疡合并出血疗效显著,止血效果明显,不良反应发生率较低,值得推广使用。
Objective To study the clinical effect of pantoprazole in the treatment of peptic ulcer combined with hemorrhage. Methods One hundred cases of peptic ulcer with hemorrhage were randomly divided into control group and observation group, 50 cases each. Two groups of basic treatment the same situation, the control group added cimetidine intravenous drip treatment, the observation group was added pantoprazole intravenous drip treatment to observe and compare the two groups. Results The total effective rate of the control group was 68.00%, the total effective rate of the observation group was 92.00%. The total effective rate of the observation group was significantly higher than that of the control group, the difference was statistically significant (P <0.05). The total incidence of adverse reactions in the observation group was 4.00%, the incidence of adverse reactions in the control group was 18.00%, and the total incidence of adverse reactions in the observation group was significantly lower than that in the control group (P <0.05). Conclusion Pantoprazole treatment of peptic ulcer bleeding with significant effect, hemostatic effect is obvious, the incidence of adverse reactions is low, it is worth promoting the use of.