本文介绍了肝素治疗慢性阻塞性支气管肺部疾病,将患者分成两組即肝素治疗組和对照組。治疗結果:用肝素靜脉注射治疗19例患者中,11例(58％)支气管痙攣緩解和粘液性分泌物阻塞的清除,其他患者有显著的改善,只有6例(22％)失敗;对照組18例中,14例(77％)用安慰剂治疗反应很小或无反应,仅2例(11％)对安慰剂有良好效果。肝素治疗組:例1,59岁,女性,因肺气肿并上呼吸道感染和呼吸困难5天入院。經吸氧、靜脉注射氨茶碱、口服土霉素、碘化鉀、强的松、茶碱等药治疗无好轉,于入院第四天病情轉坏,精神恍惚、紫紺。在上午10时靜脉注射肝素20000单位,2小时后检查呼气阻塞性罗音明显減少,下午4时呼吸困难減輕,检查其支气管痙攣亦进一步改善。晚10时又給予肝素10000单位,次晨8时患者自觉很舒适,紫绀消失,检查无呼气阻塞性罗音。又分別給予两次,各10000单位,維持稳定出院。例2,68岁,男性,因呼吸急促、虛弱、紫绀和肺心病右心衰竭入院。經常規治疗无改善,因分泌物粘 This article describes heparin in the treatment of chronic obstructive bronchopulmonary disease, which is divided into two groups, the heparinized and the control. Treatment Outcomes Out of 19 patients treated with heparin, 11 (58%) were relieved of bronchospasm and obstruction of mucinous secretions, with significant improvement in other patients, with only 6 (22%) failing; in control group 18 In our study, 14 (77%) patients treated with placebo had little or no response and only 2 (11%) had a good placebo effect. Heparin treatment group: Cases 1,59 years old, female, admitted to hospital with emphysema and upper respiratory tract infection and dyspnea for 5 days. The oxygen therapy, intravenous aminophylline, oral oxytetracycline, potassium iodide, prednisone, theophylline and other drug treatment did not improve, on the fourth day of admission to condition deterioration, trance, cyanosis. In the morning at 10 o’clock intravenous injection of heparin 20000 units, 2 hours after the examination of obstructive obstructive rales significantly reduced at 4 o’clock in the reduction of dyspnea, check their bronchospasm also further improved. At 10 o’clock in the evening he gave 10,000 units of heparin, 8 am the next morning the patient was very comfortable, cyanosis disappeared, check no obstructive rales. They were also given twice, each 10,000 units, to maintain a stable discharge. Example 2,68 years old, male, due to shortness of breath, weakness, cyanosis and cor pulmonale right heart failure hospitalization. Routine treatment without improvement, due to secretions sticky