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观察了３１例溃疡性结肠炎患者的Ｔ细胞亚群、红细胞免疫粘附功能、血清ＳＯＤ活性、补体Ｃ３水平、免疫复合物（ＣＩＣ）含量、ＭＤＡ含量、外周血ＮＫ细胞活性等有关免疫生化指标。结果表明：大肠湿热组、脾虚挟湿组ＣＤ４、ＣＤ８均低于对照组。大肠湿热组红细胞ＲＣＩＡ、ＲＣＩＣ均低于正常对照组。大肠湿热组血清ＣＩＣ、ＭＤＡ、ＳＯＤ均高于正常对照组。提示红细胞免疫粘附功能下降，ＣＩＣ和ＬＰＯ上升可作为大肠湿热型客观指标。脾虚挟湿型辅助性Ｔ细胞下降明显，红细胞免疫粘附功能正常可作为该组客观指标参考。ＣＤ４／ＣＤ８降低可作为脾虚挟湿与大肠湿热相区别的诊断指标之一。
T cell subsets, erythrocyte immune adherence function, serum SOD activity, complement C3 level, immune complex (CIC) content, MDA content and peripheral blood NK cell activity in 31 patients with ulcerative colitis were observed. . The results showed that CD4 and CD8 in the dampness-heat group and spleen-deficiency-rehmanniae group were both lower than those in the control group. The RCIA and RCIC of erythrocytes in damp heat group were lower than those in normal control group. Intestinal damp-heat group serum CIC, MDA, SOD were higher than the normal control group. Suggesting that decreased erythrocyte immune adhesion function, CIC and LPO rise can be used as an objective indicator of dampness of large intestine. Spleen-dependent wet-type T helper cells decreased significantly, erythrocyte immune adhesion function can be used as an objective indicator of the group reference. The decrease of CD4 / CD8 can be used as one of the diagnostic criteria to differentiate spleen deficiency from dampness of the large intestine.