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目的通过调查老年住院患者用药种类情况,探讨老年患者的用药安全。方法对2010年1月16日全天住院患者的用药种类进行登记,根据用药种类的多少分为3组,≤5种、6～9种、≥10种,统计各组的用药情况的分布及不良反应。结果当日住院患者493例,其中老年患者247例,另246例列为对照组。老年组用药≤5种41例(16.60%),6～9种102例(41.29%),≥10种104例(42.11%);对照组患者246例,≤5种185例(75.20%),6～9种45例(18.29%),≥10种16例(6.51%);老年组用药≥10种者构成比明显高于对照组(42.11%vs6.51%,P<0.01)。随用药种类的增多,2组的不良反应发生率均增高,但老年患者用药≥10种者用药不良反应发生率明显高于对照组(22.12%vs12.50%,P<0.05)。结论老年患者用药种类较60岁以下患者明显增多,药物不良反应也随着增多,对老年人用药安全要高度重视。
Objective To investigate the medication safety of elderly patients by investigating the types of elderly inpatients. Methods The hospitalized patients were enrolled in the hospital on January 16, 2010. All patients were divided into three groups according to the type of medication, ≤5, 6 ~ 9, ≥10, and the distribution of drug use in each group was statistically analyzed Adverse reactions. Results 493 hospitalized patients on the day, of which 247 elderly patients, the other 246 were classified as control group. There were 41 cases (16.60%) of elder patients with ≤5 diseases, 102 cases (41.29%) of 6 ~ 9 cases, 104 cases (42.11%) of ≥10 cases, 246 cases of control group (≤5 cases) There were 45 cases (18.29%) in 6 ~ 9 kinds and 16 cases (6.51%) in ≥10 kinds. The constituent ratio of ≥10 kinds in elderly group was significantly higher than that in control group (42.11% vs 6.51%, P <0.01). The incidence of adverse reactions increased with the increase of the types of drugs in both groups, but the incidence of adverse drug reactions was significantly higher in elderly patients with ≥10 drugs (22.12% vs 12.50%, P <0.05). Conclusion The type of medication in elderly patients is significantly increased compared with patients under 60 years of age, adverse drug reactions also increased with the elderly, medication safety should attach great importance.