论文部分内容阅读
目的探讨胸部CT测量的右心室(RV)与左心室(LV)容积比与超声心动图估算的肺动脉收缩压(PASP)之间的相关性。方法 104例[(72.47±13.64)岁,男性39例]病人均行胸部CT与超声心动图,根据其超声心动图PASP25mmHg(1mmHg=0.133kPa)分为两组(高血压组和正常血压组),并计算RV与LV容积比(RVV/LVV)。回归分析得出RVV/LVV与PASP具有相关性。通过计算胸部CT曲线下面积(AUC)来预测肺动脉高压。结果高血压组,平均PASP为(46.29±14.42)mmHg(29～98mmHg),且RVV/LVV与PASP之间具有显著相关性(R=0.82,P<0.001)。观察组内与观察组间RVV/LVV的相关系数为0.990和0.892。高血压组RVV/LVV为1.01±0.44(0.51～2.77),正常血压组为0.72±0.14(0.52～1.11)(P<0.05)。RVV/LVV的分界值为0.9,预测超过40mmHg肺动脉高压的敏感度和特异度分别为79.5%和90%。预测肺动脉高压的曲线下面积为0.87。结论胸部CTRV/LV容积比与超声心动图估算的PASP有很好的相关性,且用来预测超过40mmHg的肺动脉高压具有较高的敏感性和特异性。要点①胸部CT广泛应用于肺动脉高压病人。②胸部CT心室容积比与肺动脉收缩压相关。③R/L心室容积比>0.9常提示肺动脉血压>40mmHg。④常规胸部CT的有效信息有助于预测肺动脉高压。
Objective To investigate the correlation between volumetric ratio of right ventricle (RV) and left ventricular (LV) measured by chest CT and pulmonary artery systolic pressure (PASP) estimated by echocardiography. Methods Totally 104 patients [(72.47 ± 13.64) years old and 39 males] underwent chest CT and echocardiography. According to their echocardiographic PASP25mmHg (1mmHg = 0.133kPa), they were divided into two groups (hypertension group and normotensive group) , And calculate RV to LV volume ratio (RVV / LVV). Regression analysis showed that RVV / LVV was associated with PASP. Pulmonary hypertension was predicted by calculating the area under the chest CT curve (AUC). Results The average PASP in hypertension group was (46.29 ± 14.42) mmHg (29-98 mmHg), and there was a significant correlation between RVV / LVV and PASP (R = 0.82, P <0.001). The correlation coefficient of RVV / LVV in observation group and observation group was 0.990 and 0.892. RVV / LVV was 1.01 ± 0.44 (0.51 ~ 2.77) in hypertension group and 0.72 ± 0.14 (0.52 ~ 1.11) in normal blood pressure group (P <0.05). The cut-off value for RVV / LVV was 0.9, and the sensitivity and specificity for predicting pulmonary arterial hypertension over 40 mmHg were 79.5% and 90%, respectively. The predicted area under the curve for pulmonary hypertension was 0.87. Conclusions The chest volume ratio of CTRV / LV has a good correlation with the echocardiographic estimated PASP, and is used to predict pulmonary hypertension with a sensitivity and specificity of more than 40 mmHg. Points ① chest CT is widely used in patients with pulmonary hypertension. ② chest CT ventricular volume ratio and pulmonary artery systolic pressure. ③ R / L ventricular volume ratio> 0.9 often prompted pulmonary artery pressure> 40mmHg. ④ conventional chest CT information useful to predict pulmonary hypertension.