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氯硫二苯胺(Chlorpromazine)是一种新型之中枢神经系统抑制药.自1950年法国Charpentier氏首次合成本品后,各国亦相继大量生产,我国1956年起亦已开始大量生产,且此药在国内已被广泛使用.此药之药理作用多种复杂,故其临床适应症很多,因而临床各科均有使用.虽然此药毒性较低,但由于其使用指征愈来愈广,故由之引起之副作用之报告也日益增多.因氯硫二苯胺引起之体位性低血压及昏厥国内尚乏报告,作者在1959年5月间发现二例细菌性痴疾患者肌肉注射氯硫二苯胺后引起体位性低血压及昏厥,现报告其中一例,以供同道参考.
Chlorpromazine is a new type of central nervous system depressant.After the first time this product was synthesized by the French Charpentier’s in 1950, many countries have also successively mass-produced their products. Since 1956, China has begun to mass-produce it. China has been widely used.This medicine pharmacological effects of a variety of complex, so many of its clinical indications, and therefore all clinical subjects are used.Although the toxicity of this drug is low, but due to its use of indications more and more widely, so from The report of the side effects caused by it is also increasing.Due to the domestic lack of reports of orthostatic hypotension and syncope caused by chlorothiadiphenylamine, in May 1959 the author found two cases of bacterial dementia patients after intramuscular injection of chlorothiadiphenylamine Cause orthostatic hypotension and fainting, are reported in one case, for fellow reference.