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目的:观察改良新鲜厚猪皮覆盖对烧伤创面感染的影响。方法:选择烧伤创面119例,随机分为猪皮覆盖治疗组(观察组)60例和常规治疗组(对照组)59例;着重对两组治疗期间创面分泌物标本细菌鉴定结果进行对比分析。结果:对照组培养出病原菌42例(61株),占71.2%;观察组培养出病原菌30例(36株),占50.0%。对照组病原菌培养阳性率及菌株数量均显著高于观察组(P<0.05)。两组病原菌种类均以金黄色葡萄球菌、大肠埃希菌、铜绿假单胞菌和表皮葡萄球菌为主,但对照组耐甲氧西林金黄色葡萄球菌所占比例为55.6%,显著高于观察组的28.6%(P<0.05)。结论:采用新鲜猪皮覆盖创面能够显著降低创面感染率,减少耐药菌株的产生。
Objective: To observe the effect of fresh and thick pig skin covering on burn wound infection. Methods: One hundred and ninety-nine burn wounds were selected and randomly divided into 60 cases of pig skin covering treatment group (observation group) and 59 cases of conventional treatment group (control group). The bacterial identification results of wound secretions during the two groups were compared and analyzed. Results: In the control group, 42 cases (61 strains) of pathogenic bacteria were cultured, accounting for 71.2%. In the observation group, 30 cases (36 strains) were pathogenic bacteria, accounting for 50.0%. The positive rate of pathogen culture and the number of strains in the control group were significantly higher than those in the observation group (P <0.05). Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus epidermidis were the main pathogens in both groups, but the proportion of methicillin-resistant Staphylococcus aureus in control group was 55.6%, which was significantly higher than that of observation Group had 28.6% (P <0.05). Conclusion: Covering the wound with fresh pig skin can significantly reduce the wound infection rate and reduce the generation of resistant strains.